Cell Electrophysiology Simulation Environment
Details
| Size: | 0K |
| Last Update: | 2008-05-13 22:14:49 |
| Version: | 1.4.5 |
| OS Support: | Linux |
| License/Program Type: | GPL (GNU General Public License) |
| Publisher: | Sergey Missan |
| Price: | $0.00 |
Description:
Cell Electrophysiology Simulation Environment 1.4.5 is neuroscience software developed by Sergey Missan.
Cell Electrophysiology Simulation Environment (CESE) is a comprehensive framework specifically designed to perform computational electrophysiological simulations, for example, simulations of cardiac myocyte electrical activity.
Cell Electrophysiology Simulation Environment is useful for simulations of action potentials, individual ionic currents, and changes in ionic concentrations.
CESE is a cross-platform program, it runs on any system that has Java runtime environment (JRE) version 1.4 or above. It was tested on Windows, Linux, Solaris, MacOS X, and AIX.
CESE users
CESE is an integrated environment for performing computational simulations using a variety of electrophysiological models.
At this stage CESE allows creation and execution of the single-cell models (containing both Hodgkin-Huxley (HH) and Markovian current formulations). Models of electrical activity of cardiac myocytes with source code are included in the CESE distribution. We hope to extend the number of available models, and add certain neuronal models in the future.
The main strength of CESE is in its uniformity &65533; a program interface remains the same for different types of models. You can easily switch between models and compare simulation outputs. Model parameters can be modified, selected for output and/or clamped in the same, standard way.
CESE extends the conventional electrophysiological meaning of the "voltage clamp". You can clamp virtually any model variable, including voltage (membrane potential), total or individual ionic currents, ionic concentrations, temperature, gating variables, etc. The clamping commands can be complex piece-wise functions, individually set for the model variable of interest. This opens endless possibilities for the exploration of complex model behavior.
CESE provides simple, but efficient data visualizations. Simulation results can be presented in the graphic and tabulated forms. Plots can be customized, and regions of interest zoomed.
Even though CESE was not designed to be a data analysis tool, you can generate current-voltage relationships (I-Vs) and calculate statistical parameters for a given signal within the program. You can export your data to ASCII, Axon Text File (ATF), and NetCDF formats to continue analysis in your favorite package.
CESE developers
CESE was created from the ground up to incorporate the best programming practices available to Java developers, both in terms of user interface consistency and code clarity and reuse. Wherever possible, CESE rely on available Java APIs (for example Java2D, JavaBeans, JAXP) to simplify the code.
Model creation requires a number of house-keeping functions to be coded &65533; these include ODE integrators, routines for handling model parameters, saving/restoring model state, visualizing simulation results, etc. CESE provides you with implementation for these routines, hence, you can concentrate on writing the code for concrete ionic current(s), and CESE will handle the rest.
CESE is not trying to create complicated programming frameworks on its own &65533; rather, it utilizes core Java APIs. For example, models are Java components conforming to the JavaBeans specification. We use XML to specify clamping commands, and Java object serialization to save/restore model parameters.
What's New in This Release:
This release has switched to Java 1.5 (5.0).
There are massive updates to multithreading to improve stability, many updates to cursors and data analysis, optimized plots, and much more.
Cell Electrophysiology Simulation Environment 1.4.5 supports english interface languages and works with Linux.
Downloading Cell Electrophysiology Simulation Environment 1.4.5 will take if you use fast ADSL connection.
0 comments
Add to
Cell Electrophysiology Simulation Environment Version History
Related Software
|
|
From category: Mathematics |
| Universal tool for statistical analysis and modeling of experimental and market data. Support import data from variety of data sources. Statistical schemes cover all major data modeling operations. Cr... |
|
|
From category: Electronic-Design-Automation |
| Balsa Asynchronous Synthesis System 3.5 is electronic design automation ( software developed by Advanced Processor Technology. Balsa project is an asynchronous circuit synthesis system. Balsa is bu... |
|
|
From category: Visualization |
| JDiveLog is a logbook for scuba diving.... |
|
|
From category: Mathematics |
| Giac/Xcas is a free computer algebra system for Windows, Mac OS X and Linux/Unix.... |
|
|
From category: Artificial-Intelligence |
| MDR was developed to facilitate the detection, characterization, and interpretation of gene-gene interactions or epistasis.... |
|
|
From category: Visualization |
| Cvtool is a general-purpose computer vision tool.... |
|
|
From category: Medical-Science-Apps |
| FlipDCD 1.1 is medical science apps. software developed by Jim Phillips. FlipDCD is a small utility for reversing the endianism of binary DCD trajectory files from Charmm, and NAMD. This can be use... |
|
|
From category: Electronic-Design-Automation |
| CAM Expert 2.0.4.8 is electronic design automation ( software developed by Andrew Mustun. CAM Expert is a CAM extension of QCad. It features automatic creation of G-Code, HP/GL and many other forma... |
|
|
From category: Bioinformatics |
| BioJava 1.30 is bioinformatics software developed by Thomas Down. BioJava is an open-source project dedicated to providing a Java framework for processing biological data. It include objects for ma... |
|
|
From category: Mathematics |
| A practical lambda-calculator 2.2 is mathematics software developed by Oleg. A practical lambda-calculator is a normal-order evaluator for the untyped lambda-calculus, extended with convenient comm... |
|
|
From category: Bioinformatics |
| Java Machine Learning Library is a set of reference implementations of machine learning algorithms.... |
|
|
From category: Electronic-Design-Automation |
| Electronic Design Automation - Index 1.0 is electronic design automation ( software developed by Baxeno. The system can be used in the electronic world to keep track of your: Schematic, Printed Cir... |
|
|
From category: Bioinformatics |
| Array Designer 4.11 is bioinformatics software developed by PREMIER Biosoft International. Array Designer project can help design thousands of efficient, highly specific oligos to make microarrays... |
|
|
From category: Mathematics |
| JACAL is an interactive symbolic mathematics program.... |
|
|
From category: Mathematics |
| cgtkcalc is a simple scientific calculator for complex numbers.... |
Leave a comment